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Thomas C. Chen , MD, PhD Co-Director, USC/Norris Neuro-Oncology Program Thomas C. Chen, M.D., Ph.D., Neurosurgeon, specializes in neuro-oncology, treating a wide range of brain and spinal cord tumors. His clinical and research interests are three pronged: 1) using neuronavigational instrumentation and frameless strategic devices to localize brain tumors prior to open surgery; 2) performing clinical trials for the treatment brain tumors; 3) conducting translational lab research focusing on gliomas. Dr. Chen received his medical degree from the University of California, San Francisco, and completed his surgical internship and neurosurgical residency at USC, where he also earned his doctorate in experimental pathology. He then completed a one-year spine fellowship at the Medical College of Wisconsin before joining the USC faculty in 1997. He is currently a tenured associate professor of neurosurgery and pathology. Research Interests The research in our laboratory is focused on translational research for malignant gliomas, We are currently working on combining signal transduction modulation (cAMP/protein kinase A pathway) of malignant gliomas using chemotheraphy, with genetic manipulation via gene therapy. Gene therapy efforts have been directed towards improving targeting of glioma cells and glioma endothelial cells using a targeted adenovirus. The eventual combination of chemotherapy and gene therapy may prove to be a viable clinical treatment option for patients with malignant gliomas.
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CONTACT INFORMATION 1520 San Pablo St. |
